All studies
Percentage of Heavy Drinking Days Following Psilocybin-Assisted Psychotherapy vs Placebo in the Treatment of Adult Patients With Alcohol Use Disorder
Key finding
Psilocybin-assisted therapy significantly reduced heavy drinking days compared with active placebo over 32 weeks, suggesting potential for treating alcohol use disorder.
- Institution
- NYU Langone
- Design
- Randomized, double-blind, placebo-controlled trial
- Sample size
- 95 participants
- Intervention
- Two psilocybin doses with psychotherapy vs. antihistamine active placebo
- Year
- 2022
- Condition
- Alcohol use disorder
Limitations
Functional unblinding likely; the psychotherapy component makes it hard to isolate the drug effect; needs replication in larger trials.
One of the strongest controlled signals for psilocybin beyond mood disorders, extending the evidence into addiction treatment with a relatively large, placebo-controlled design.
Read the primary source Our breakdown: Psilocybin for Treatment-Resistant Depression: What the Research Actually Shows
Summary written by MMI Editorial for clarity. Always consult the primary source for full methodology and results. Confidence rating reflects our assessment of evidence strength.